In a new study published in Genes & Development, research led by Dr. Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for Molecular Genetics and Charité in Berlin demonstrates how different regulatory genetic elements coordinate the temporal activity of a key developmental gene. Their findings likely explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown.
Continue Reading this article here
