Inconsistent use of some GLP-1 weight-loss medications, like Ozempic and Wegovy, may significantly lessen their effectiveness, according to a new preclinical study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, published in the Journal of Clinical Investigation Insight, showed that each time overweight mice stopped and restarted GLP-1s, they dropped less and less weight compared to their original weight-loss.
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