A new study offers fresh insight into Alzheimer’s disease by looking beyond the brain and focusing on metabolic health, particularly obesity. The Houston Methodist-led study moves beyond the traditional view of obesity as a general health risk and investigates how obesity-related changes in body fat can send harmful signals to the brain, disrupting brain immune function, thereby worsening Alzheimer’s pathology. Co-led by Stephen Wong, Ph.D., the John S. Dunn Presidential Distinguished Chair in Biomedical Engineering and Li Yang, Ph.D., research associate in the Chao Center for BRAIN at Houston Methodist, the study appears in Molecular Neurodegeneration.
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