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New light-based technique reveals the inner workings of cells

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Human cells adjust to ever-changing conditions while preserving internal states necessary for survival, but exactly how they achieve both adaptability and stability remains unclear. For the first time, researchers, including those from the University of Tokyo, used a light-based technique called Raman spectroscopy to create snapshots of the entire protein landscape inside an E. coli cell in a nondestructive manner.

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