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How mRNA cancer vaccines still destroy tumors when a key immune cell is missing

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The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel Prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, small-cell lung cancer and bladder cancer, among others, opening the door to new ways of preventing and treating the disease.

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