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Home Health Gene-screen strategy separates Parkinson’s promoters from protectors, revealing new drug targets

Gene-screen strategy separates Parkinson’s promoters from protectors, revealing new drug targets

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A novel strategy that combines computational and experimental approaches has allowed researchers at Baylor College of Medicine and the Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital to distinguish alterations in gene function that contribute to Parkinson’s disease from those that protect from the condition. The study, published in Neurobiology of Disease, revealed novel risk factors and previously unrecognized therapeutic targets, offering hope for a future in which effective therapies will be available to prevent, slow down or stop this devastating disease.

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