Every year, about 3 to 5 million people in the EU and the U.S. suffer a traumatic brain injury (TBI). In most cases, it is a mild brain injury (mTBI) due to a closed head injury (CHI) caused by falls, traffic accidents, contact sports, or violence. Although the symptoms of mTBI may resolve within days or weeks, up to 20% of those affected suffer from persistent physical, cognitive, and behavioral impairments, leading to a reduced quality of life and an increased risk of neuropsychiatric disorders, including mood disorders and dementia.
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