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B-cell clusters inside kidneys mark faster diabetic disease progression, new maps reveal

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A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells—specifically B cells—that are linked to faster disease progression. The findings could help guide more targeted treatments in the future, according to study results led by researchers at the Perelman School of Medicine at the University of Pennsylvania and published in Nature.

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