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A major cancer protein hijacks RNA editing, exposing a new weakness in prostate tumors

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Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new layer of genetic regulation that could reshape how certain cancers are treated. In a new study published in Nature Communications, investigators found that EZH2—a protein long recognized for its role in modifying DNA-packaging histones—also plays a direct and previously unknown role in RNA editing in prostate cancer.

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