When someone is diagnosed with colorectal cancer—which includes both colon and rectal cancers—many people immediately think “surgery.” And it’s true that surgery plays a central role in treatment for most patients. But whether it comes first, and what it entails, depends on several factors, especially where the cancer is located, how far it has grown into surrounding tissues, and whether it has spread, explains Eric Dozois, M.D., chair of colon and rectal surgery at Mayo Clinic in Minnesota.

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