Obesity is a known risk factor for cardiovascular disease, but people’s weights can shift over time, and little is known about the cumulative impact of excess weight. New research from investigators at Mass General Brigham shows that long-term exposure to excess weight is a stronger predictor of cardiovascular risk than body mass index (BMI) at a single point in time, with the effect strongest in younger people. The results, published in PLOS One, suggest that losing weight and decreasing excess weight exposure may decrease a person’s cardiovascular risk.
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