i-DNA ‘peek-a-boo structures’ form in living cells and regulate genes linked to cancer

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DNA’s iconic double helix does more than “just” store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown that one such structure, known as i-DNA, not only forms in living cells but also acts as a regulatory bottleneck linked to cancer.

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