Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial role in the hearing process. Loss of otoferlin or impairment of its function causes a frequent form of congenital deafness. The results, published in the journal Science Advances, mark a milestone after more than two decades of research on otoferlin at Göttingen Campus and contribute to optimizing the first gene therapies for the treatment of deafness.
