Soft ‘cyborg’ cardiac patches could improve stem cell heart repair

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Heart muscle cells grown from patient stem cells—known as human induced pluripotent stem cell–derived cardiomyocytes, or hiPSC-CMs—are a promising way to repair hearts damaged by heart attacks and heart failure. But transplanted hiPSC-CMs often have trouble syncing to the rhythm of native heart cells, which can cause dangerous arrhythmias after transplantation.

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