Zenocutuzumab (Bizengri), a bispecific antibody that targets human epidermal growth factor receptor 2 (HER2) and HER3, led to responses in more than a third of patients with neuregulin 1 (NRG1)-positive cholangiocarcinoma, according to results from the phase II eNRGy clinical trial presented at the AACR-NCI-EORTC International Conference on Molecular Targets, held October 22–26.
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