Inflammasome found to drive male-specific bone loss in gum disease

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A study out of the University of North Carolina at Chapel Hill has unveiled new insights into the inflammatory processes behind periodontitis, a common and debilitating gum disease. Research conducted by UNC Adams School of Dentistry’s Julie Marchesan, DDS, Ph.D., and UNC School of Medicine’s Jenny Y. Ting, Ph.D., found that a part of the immune system called the inflammasome plays a key role in disease development, and that blocking this system prevents bone resorption only in males.

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